Phenytoin Sodium
The highly soluble sodium salt form of phenytoin, engineered exclusively for rapid-onset parenteral administration during critical status epilepticus protocols.
CAS Number
630-93-3
Formula
C₁₅H₁₁N₂NaO₂
Mol. Weight
274.25 g/mol
Grade
BP / EP / USP
Product Overview
Phenytoin Sodium is the pharmaceutically enhanced, highly soluble sodium salt iteration of the foundational anticonvulsant, Phenytoin. Its significantly elevated aqueous solubility makes it absolutely vital for formulation into parenteral (injectable) solutions, granting clinicians the crucial ability to rapidly achieve therapeutic plasma levels during acute neurological crises.
As a global pharmaceutical leader, Jay Overseas guarantees the supply of this critical API from ultra-modern, strictly-audited, WHO-GMP certified facilities. We meticulously manage endotoxin profiling and microbial data to ensure our Phenytoin Sodium perfectly meets the stringent demands of injectable manufacturing lines worldwide.
Parenteral Superiority
Meticulously suppressed endotoxin capabilities for safe IV integration.
Aqueous Optimization
Engineered directly for rapid-dissolution compounding in sterile environments.
API Snapshot
Mechanism of Action (Injectable Focus)
Rapid Systemic Assimilation
Delivered intravenously or intramuscularly, it utilizes its sodium-derived solubility to instantly enter the bloodstream, bypassing standard gastrointestinal absorption delays.
Voltage-Gated Suppression
Upon crossing the blood-brain barrier, it immediately targets and binds specifically to the inactive state of voltage-gated neuronal sodium channels.
Excitatory Collapse
This highly rapid binding aggressively prevents high-frequency repetitive cellular firing, structurally suppressing the continuous cycle of status epilepticus instantly.
Therapeutic Applications
Status Epilepticus
The primary rapid-response injectable intervention to halt life-threatening, continuous seizure activity.
Neurosurgical Prophylaxis
Prophylactic administration to prevent seizures during and acutely following major neurosurgical procedures.
Severe Tonic-Clonic Therapy
Immediate suppression of extreme generalized tonic-clonic episodes when oral routes are wholly restricted.
Acute Trauma Management
Crucial early-stage neuro-stabilization following profound head trauma or acute cerebral events.
Clinical Advantages & Value Proposition
Phenytoin Sodium presents the uncompromising solubility required by modern intensive care units while maintaining the proven antiepileptic efficacy of standard phenytoin.
Significantly higher aqueous solubility compared to free-base phenytoin
Optimized specifically for critical intravenous (IV) and intramuscular (IM) emergency administration
Rapid therapeutic onset essential for halting profound status epilepticus
Engineered with controlled impurity profiling accommodating intensive parenteral standards
Long half-life sustaining plasma concentrations after successful acute interventions
Cost-effective yet highly purified synthesis yielding unmatched clinical reliability
Manufacturing Excellence
Sourced from advanced, extensively-audited WHO-GMP certified facilities, our Phenytoin Sodium undergoes intense testing explicitly for endotoxin presence and bioburden to perfectly satisfy parenteral regulations globally.
Parenteral Grade
Injectable Synthesis Cleared
Documentation
Complete Technical Pack
Why Choose Our Phenytoin Sodium
Regulatory Excellence
Products sourced unequivocally from facilities with USFDA DMFs filed, WHO-GMP certifications, and comprehensive compliance with BP, EP, and USP mandates.
Injectable Grade Purity
Engineered with ultra-low limits for endotoxins and microbial counts, specifically tailored to support highly sensitive parenteral (injectable) formulations.
Reliable Global Supply
Consistent global availability backed by highly efficient logistics into regulated and emerging markets worldwide.
Complete Documentation
Full and transparent technical packages available, including DMF access, multi-zone stability monitoring data, and extensively validated Certificates of Analysis.
Related CNS APIs
Packaging Standard
Double LDPE/HDPE inner bags secured inside robust fiber drums. Meticulous export-worthy sealing for injectable-grade stabilization.
Storage Protocol
Store securely at controlled room temperature 15–30°C (59–86°F). Critical absolute protection from prolonged light exposure and moisture.
Validated Shelf Life
Maintains optimal stability profiling. Shelf life is confirmed strictly according to highly regulated multi-zone stability monitoring.
Source Injectable-Grade API
Contact our commercial team today for highly-controlled Phenytoin Sodium sampling, strict regulatory documentation profiling, and advanced supply analytics.
Legal Disclaimer: Phenytoin Sodium API is a highly regulated therapeutic substance. The product documentation, CoAs, and regulatory support detailed above are exclusively available for licensed pharmaceutical manufacturing entities and authorized research divisions under proper legal importation compliances. This API is not a finished dosage form.