Allopurinol API
A premium small molecule purine analog functioning as a critical xanthine oxidase inhibitor, driving hyperuricemia and gout management protocols globally.
CAS Number
315-30-0
Formula
C₅H₄N₄O
Mol. Weight
136.11 g/mol
Grade
USP / EP / BP / IP
Product Overview
Allopurinol is a profoundly effective purine analog that strictly inhibits xanthine oxidase, decisively reducing the overall production of pathological uric acid in the body. It relies on a proven mechanism extensively utilized in long-term critical management of hyperuricemic conditions, including advanced gout and oncology-related hyperuricemia.
As a global pharmaceutical leader, Jay Overseas exclusively focuses on securing Allopurinol API from validated, thoroughly audited WHO-GMP facilities. We ensure uncompromising batch consistency, flawless traceability, and continuous, uninterrupted commercial supply for complex dosage formulation and global dossier development projects.
Analytical Precision
Strictly controlled formulation matrices mitigating supply disruptions.
Dossier Alignment
Ready specifically for advanced CTD/ACTD module submissions globally.
API Snapshot
Mechanism of Action (Technical)
Enzymatic Inhibition
Allopurinol actively and decisively inhibits xanthine oxidase, the critical enzyme responsible for the conversion of hypoxanthine to xanthine.
Xanthine Conversion Blockade
It further acts to powerfully block the secondary conversion phases mapping from xanthine directly into uric acid.
Serum Uric Acid Reduction
This targeted bi-modal blockade results in a dramatically decreased overall serum uric acid baseline level systemically.
Soluble Substrate Elevation
Due to the inhibition, there are successfully increased levels of the more highly soluble hypoxanthine and xanthine, which are then much more readily eliminated naturally.
Therapeutic Applications
Chronic Gout
Primary foundational management and profound control of chronic gout instances.
High Cell Turnover Hyperuricemia
Control of hyperuricemia strictly associated with high cell turnover conditions, such as specific oncology treatments.
Nephropathy Prevention
Critical prevention of uric acid–related nephropathy protecting renal functional longevity.
Stone-Forming Tendencies
Management of recurrent uric acid and calcium oxalate stone-forming tendencies.
Regulatory & Quality Highlights
Our Allopurinol pipeline guarantees compliance with WHO-GMP parameters alongside comprehensive ICH guideline adherence. We establish long-term collaborations for post-approval variations and active assistance with country-specific query resolutions safely.
Purity Support
Validated Reference Standards
Pharmacopeial Quality
USP / EP / BP / IP Cleared
Why Source From Jay Overseas
A trusted pharmaceutical trading partner ensuring uncompromising quality and supply continuity.
Regulatory Confidence
Supplied with complete regulatory documentation including COA, MSDS, stability data, and pharmacopeial compliance dossiers suitable for stringent global submissions.
Consistent Quality
High-purity API with intensely controlled impurity profiles and robust analytical support, suitable for solid oral dosage development and lifecycle requirements.
Supply Flexibility & Risk Mitigation
Flexible MOQ options and forward planning alongside a multi-source strategy and strict vendor qualification to completely minimize supply disruptions.
Global Reach & Technical Support
A dedicated, export-ready supply chain serving regulated and semi-regulated markets, fully backed by an expert regulatory team for global registration needs.
Logistics & Handling
Palletized shipments with stringent tamper-evident sealing. Double LDPE inner bags in HDPE drums. Support for both sea and air freight per client dictates.
Storage Conditions
Store exclusively in a cool, dry place securely. Rigorously protect from both moisture and light. Keep the primary container tightly and properly closed.
Validated Shelf Life
Extended shelf life formally validated at 48 – 60 months, supported inherently by ICH compliant stability parameters aligning globally.
Construct Your Dosage Portfolio
Speak with our regulatory and commercial teams today for rapid dispatch of sampling batches, flexible MOQ structures, and immediate access to full regulatory submissions.
Legal Disclaimer: Allopurinol API is intended strictly for professional manufacturing, generic formulations, and authorized research division purposes. The product documentation, CoAs, and regulatory support detailed above are exclusively available for licensed pharmaceutical entities under relevant legal importation compliances. This active ingredient is not formatted for direct consumer consumption.