3-Dibenzyl
Phosphono
A fundamentally versatile organophosphorus intermediate engineered explicitly driving complex antiviral analog development and deep anticancer active ingredient progression dynamically.
CAS Number
42122-33-2
Formula
C₁₄H₁₅O₃P
Mol. Weight
262.24 g/mol
Min. Purity
≥ 97.0%
Precursor Intelligence Overview
3-Dibenzyl Phosphono constitutes an incredibly highly valued organophosphorus compound engineered specifically featuring dual benzyl protecting groups heavily bonded onto its exact phosphonate structural moiety. This precisely configured molecular arrangement serves exclusively to enforce heavy foundational stability deeply inside extremely complex multi-stage synthesis operations directly generating nucleotide analogues.
Mapped actively against intense international production networks, Jay Overseas executes the completely flawless delivery of this sensitive intermediate explicitly avoiding synthetic formulation delays natively. By heavily leveraging advanced ³¹P NMR validation matrices, the dense reactive intermediate flawlessly retains absolute structural immutability reliably feeding the global commercial antiviral/anticancer industry continuously.
Moiety Reactivity Integration
Allows structurally pristine subsequent integration stripping strictly under mild control operations.
Total Impurity Containment
Forces absolute minimums aggressively maintaining related substances uniformly beneath NMT 0.5% absolutely.
Specification Snapshot
Precision Phosphorylation Architecture
Catalyzed Phosphorylation
Begins essentially relying natively upon ultra-high purity starting materials structurally forcing heavily controlled robust phosphorylation alignments strictly securely.
Benzyl Conjugation
Seamlessly operates heavily restricting the sensitive phosphonate reactive grouping specifically via structural benzyl moiety bonds deeply executing immense synthesis stability.
Advanced Crystallization
Immediately driven violently stripping trace impurities totally completely validating absolute ³¹P element tracking mapping perfectly across international compliance metrics.
Applications in Deep API Flow
Antiviral Formulations
Acts purely as a frontline active intermediate explicitly yielding heavily synthesized nucleotide analogue matrices structurally.
Anticancer Prodrugs
Seamlessly operates as an advanced foundational phosphonate building block powering massive modern anticancer generation pipelines.
Enzyme Inhibitor Integration
Supports highly complex molecular architectures acting as an essential precursor powering biological probes and deep inhibitors natively.
Advanced Matrix Analytics
Provides immense absolute stability fueling aggressive highly multi-step synthesis R&D environments strictly securely.
Purity Extrapolation & Analytic Depth
Functions entirely backed by deep structural analytical elemental measurements ensuring flawless stable execution natively matching incredibly stringent global pharmaceutical pipeline architecture fully securely.
Displays extraordinary chemical baseline stability actively mitigating molecular degradation across deep localized commercial storage networks
Manufactured holding totally superior batch-to-batch execution thresholds matching strict multi-ton scale production effortlessly
Engineered using a tightly constrained phosphorylation matrix pushing pristine limits utilizing exceptionally high-purity raw material sourcing
Supported fundamentally by exhaustive deep analytical documentation files fully guaranteeing absolute global regulatory DMF conformity
Chemical Specifications Matrix
Robust Pharmaceutical Grade Phosphonate Target Parameters
| Sr. | Diagnostic Parameter | Target Specification Limit |
|---|---|---|
| 1 | Description | Clear to pale yellow viscous liquid or white to off-white solid |
| 2 | Solubility | Soluble in chloroform, DCM, THF; sparingly soluble in water |
| 3 | Identification (FTIR) | IR spectrum matches reference standard perfectly |
| 4 | Identification (NMR) | ¹H NMR and ³¹P NMR absolutely confirm complex molecular structure |
| 5 | Refractive Index | 1.540 – 1.550 (at exactly 20°C) |
| 6 | Specific Rotation | Verified and reported value internally (if chiral presence detected) |
| 7 | Water Content (KF) | Strictly not more than 0.5% |
| 8 | Related Substances (HPLC) | Any single impurity: NMT 0.5% | Total overall impurities: NMT 2.0% |
| 9 | Heavy Metals | Tight restriction NMT 10 ppm |
| 10 | Phosphorus Content | 11.5% – 12.5% (Theoretical target: 11.81%) |
| 11 | Residual Solvents | Fully compliant with rigorous ICH Q3C guidelines |
| 12 | Assay Execution (HPLC/NMR) | 97.0% – 102.0% |
Why Sourcing with Jay Overseas Fortifies Operation
We actively govern incredibly strict logistical containment bridging complex compliance chains natively.
Global Distribution Infrastructure
Engineered through complete vertical chain traceability routing massive bulk quantities efficiently into international pharmaceutical pipelines.
Validated GMP Excellence
All molecular synthesis completely transpires natively inside strict WHO-GMP certified facilities enforcing profound optimization matrices.
Absolute Structural Purity
Consistent base purity bounds strictly held at ≥97.0% enforcing highly controlled impurity baselines actively preventing synthesis degradation.
Specialized Media Handling
Flawlessly protected utilizing incredibly high-quality HDPE internal sealing mechanisms rigorously fitted flawlessly directly against absolute heavy induction aluminum shielding.
Sensitive Thermal Control
Routinely executed deeply securing thermal variables entirely between rigorous 2°C – 8°C boundaries pushing structural isolation preventing severe chemical reactivity breakdown continuously.
Valid Core Integrity Limit
Powerfully holds immense functional latency consistently preventing deep molecular degradation inherently retaining its full strict 36 month duration baseline totally cleanly.
Initiate API Synthesis Orders
Extract detailed extreme precision ³¹P NMR structural verifications, bypass commercial formulation bottlenecks, and trigger active global chain fulfillment pipelines instantly natively today.